Comparison between quantitative mRNA expression level of selected genes in nine original tumors and in their corresponding xenografts measured by quantitative RT-PCR
Tumors | ERα | PR | HER1 | HER2 | HER3 | HER4 | KI67 | Cyclin E1 | Cyclin E2 |
---|---|---|---|---|---|---|---|---|---|
HBC-2* | 11 | 11 | 158 | 1,035 | 138 | 774 | 5,600 | 557 | 4,810 |
HBCx-2† | 0 | 1 | 0 | 970 | 46 | 267 | 6,514 | 425 | 5,508 |
HBC-4 | 87 | 7 | 2,646 | 551 | 69 | 7 | 3,105 | 569 | 2,528 |
HBCx-4 | 325 | 0 | 5,221 | 460 | 170 | 12 | 8,045 | 1,094 | 5,580 |
HBC-5 | 64 | 3 | 421 | 14,318 | 357 | 108 | 1,547 | 473 | 822 |
HBCx-5 | 986 | 0 | 1 | 78,607 | 2,738 | 1,193 | 15,326 | 2,355 | 10,614 |
HBC-6 | 6 | 0 | 577 | 671 | 96 | 113 | 3,972 | 982 | 5,766 |
HBCx-6 | 34 | 0 | 1,500 | 1,480 | 192 | 106 | 4,507 | 1,842 | 5,683 |
HBC-9 | 35 | 23 | 770 | 987 | 358 | 120 | 3,174 | 782 | 2,740 |
HBCx-9 | 2 | 0 | 1,365 | 1,762 | 1,074 | 75 | 11,484 | 4,266 | 15,412 |
HBC-10 | 207 | 2 | 618 | 1,084 | 458 | 1 | 15,913 | 3,525 | 4,601 |
HBCx-10 | 190 | 0 | 673 | 1,622 | 1,119 | 2 | 16,405 | 3,163 | 6,111 |
HBC-13 | 58 | 2 | 151 | 20,884 | 338 | 1,435 | 2,202 | 511 | 2,362 |
HBCx-13 | 44 | 4 | 320 | 30,595 | 956 | 1,468 | 1,140 | 458 | 5,031 |
HBC-12 | 8 | 18 | 918 | 844 | 737 | 218 | 2,678 | 412 | 1,324 |
HBCx-12 | 67 | 1 | 954 | 2,248 | 1,960 | 45 | 7,040 | 537 | 5,285 |
HBC-16 | 26 | 2 | 1,179 | 985 | 441 | 90 | 1,953 | 570 | 1,765 |
HBCx-16 | 1 | 10 | 3,138 | 7,119 | 976 | 124 | 7,055 | 1,730 | 3,281 |