Table 5.

Characteristic features of the triple-negative phenotype

Often present as interval cancers
Weak relationship between tumor size and node status
Rapid rise in risk of recurrence following diagnosis
Peak risk of recurrence at 1-3 y
Distal recurrence rarely preceded by local recurrence
Local recurrence not predictive of distal recurrence
Increased mortality rate first 5 y
Majority of deaths occur in first 5 y
Rapid progression from distant recurrence to death