Table 1.

Peptides from WT1 that are predicted to bind to HLA-DRB molecules

NameSequenceScore*
DRB1*0101DRB1*0301DRB1*0401DRB1*0701DRB1*1101DRB1*1501
423RSDELVRHHNMHQRNMTKL151720141024
328PGCNKRYFKLSHLQMHSRKHTG281128182520
122SGQARMFPNAPYLPSCLES221822161618
122A1SGQAYMFPNAPYLPSCLES§271722181618
Frequency in Caucasian population (49)18.517.723.626.217.019.9
  • * SYFPEITHI prediction software available at http://www.syfpeithi.de.

  • Peptide encompasses the sequence reported by ref. 29 (WT1 amino acids 331-345).

  • Peptide encompasses the sequence reported by Kobayashi et al. (WT1 amino acids 124-138; ref. 31).

  • § Residue Y in bold represents a modification from the native 122 sequence.