Table 1.

Baseline characteristics of patients enrolled (13 patients)

CharacteristicNumber
Age, median (range)56 (42-81)
Women11
Histology
    Adenocarcinoma11
    NSCLC2
Smoking history
    Never smokers7
    ≤15 pack-y4
    >15 pack-y2
Time from diagnosis of metastatic disease (mo)
    Median (range)20 (8-91)
Previous treatment
    Erlotinib6
    Gefitinib7
Time on erlotinib or gefitinib (mo)
    Median (range)16 (8-79)
EGFR
    L858R*2
    Exon 19 deletion6
    Not available5
  • * On biopsy material obtained after treatment with gefitinib, one patient had both L858R and T790M.