Table 2.

Expression levels of markers in 103 breast tumors

Total levels, N (%)Hscore [cutoff, 25], N (%)
EGFR35 (33.8)
p-EGFR18 (17.4)18 (17.4)
HER223 (22.3)
p-HER211 (10.7)11 (10.7)
p-ERK1/290 (87.3)48 (46.6)
p-Akt61 (59.2)48 (46.6)
p-4EBP190 (87.3)61 (59.2)
pp70S6K180 (77.7)39 (37.8)
p-S680 (77.7)34 (32.9)
  • NOTE: Total expression was described for all markers. The Hscore cutoff of 25 was considered overexpression, based on median expression in nontumoral breast epithelium.