Table 1.

KRAS mutation profile in HNPCC-MSS CRC cases

Nucleotide changeAmino acid changeNo. (%) [N = 23]
GGT to GATG12D9 (39.1)
GGT to GTTG12V5 (21.7)
GGT to GCTG12A3 (13.0)
GGT to AGTG12S1 (4.3)
GGT to TTTG12F or G12C/V*1 (4.3)
GGC to GACG13D4 (17.4)
  • * We cannot distinguish if the observed change represents a novel mutation or the presence of two clonal populations.