Table 2.

Mutations found at the APC MCR in HNPCC-MSS tumors

Tumor IDAPC Somatic mutation*β-Catenin immunohistochemistryKRAS somatic status
T159A3954 del TAAT1303×NucleusWT
T160BG3982T1309×NucleusGTT GGC (G12V)
T108A3983 del AAAGA1312×NucleusWT
T137B3982 del AAAAG1312×NucleusWT
T43B4034 del 38 bp1328×NucleusAGT GGC (G12S)
T43A4091 del AA1353×MembraneWT
T122A4246 del GA1408×NucleusWT
T137A4249 del AG1408×MembraneWT
T142B4279 ins TG1415×NucleusGGT GAC (G13D)
T17AT4520G1488×MembraneWT
T98BS 1360 FNucleusGTTGGC (G12V)
T112AV 1323 INucleusWT
  • * According to Genbank accession no. NM_000038.