Table 5.

Joint effects of unfavorable genotypes in case patients and control subjects in Caucasians

No. unfavorable genotypesCases/controlsOR (95% CI)*
Reference group4/15Reference
1197/2083.82 (1.24-11.80)
2229/2413.73 (1.21-11.49)
3106/944.70 (1.49-14.78)
416/97.55 (1.89-30.17)
Ptrend0.002
  • * Adjusted for age, gender, smoking status, and pack-years.

  • Reference group: CCND1 G870A: GG+GA, p53 intron 6: GG, STK15 F31I: TT, and p27 5′ UTR: CC.