Table 5.

Overall tumor response

Dose (mg/kg)nTumor response, n (%)
CR*PRSDPD
I.v. arm
    0.0431 (33)1 (33)1 (33)
    0.1631 (33)2 (67)
    0.3275 (71)1 (14)
    0.4861 (17)5 (83)
S.c. arm
    0.0131 (33)2 (67)
    0.0431 (33)2 (67)
    0.0874 (57)3 (43)
    0.1661 (17)5 (83)
Extended s.c. arm
    0.24122 (17)4 (33)3 (25)3 (25)
  • Abbreviations: CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease.

  • * Complete response was unconfirmed in two patients.