Table 3.

Prostate cancer recurrence status in patient groups and substratified by XIAP protein expression category

Patient groupTotal count (n)Total % censored*Low XIAP % censored (count, n)High XIAP % censored (count, n)
All patients1926458 (158)94 (34)
    Low grade1127974 (89)100 (23)
    High grade804336 (69)82 (11)
    Organ confined§1007773 (78)91 (22)
    Not confined925042 (80)100 (12)
  • * Proportion of patients who reach the end of PSA follow-up without evidence of recurrence. Recurrence = PSA elevation raising >0.2 ng/mL status post–radical prostatectomy.

  • Pooled mean XIAP intensity dichotomized: low ≤1.8; high >1.8 on a 0 to 3 scale.

  • Low grade = Gleason score of 2 to 6; high grade = Gleason score of 7 to 9 (there are no cases of Gleason 10 in this cohort).

  • § Organ confined = no capsular extension and/or seminal vesicle and/or lymph node involvement. Margins are negative.