Table 2.

Association between demographic/clinicopathologic characteristics and methylation of multiple genes

Clinical characteristicsCIMP sum
P*
0-1
2+
n (%)n (%)
Sex
    Female48 (31)14 (50)0.08
    Male106 (69)14 (50)
Age (y)
    ≤6578 (51)13 (46)0.84
    >6576 (49)15 (54)
Race
    White135 (88)26 (93)0.55
    Black10 (6)0 (0)
    Hispanic9 (6)2 (7)
Primary tumor site
    Distal107 (69)12 (43)0.01
    Proximal47 (31)16 (57)
Liver metastases
    No34 (22)8 (29)0.47
    Yes120 (78)20 (71)
Nodal metastases
    No100 (65)13 (46)0.09
    Yes54 (35)15 (54)
Performance status
    083 (54)9 (32)0.08
    163 (41)17 (61)
    28 (5)2 (7)
  • * From Fisher's exact test.