Table 6.

Multivariate stepwise forward regression analysis with daily spontaneous physical activity or maximum exercise capacity as dependent factors versus measures of systemic inflammation (blood hemoglobin concentration, CRP, serum albumin) and nutritional state (weight loss, FFM) as independent variables in cancer patients

Independent variablesCoefficientP
Weight loss (%)SPA−8.7<0.0006
MENS
HbSPA−3.7<0.04
MENS
CRPSPA−1.4<0.04
MENS
Serum albuminSPANS
ME3.0<0.0001
FFMSPANS
ME2.0<0.0001
PF (SF-36)SPA2.9<0.004
ME0.8<0.0001
BP (SF-36)SPA1.8<0.05
ME−0.5<0.001
  • NOTE: The multivariate regressions were significant at P < 0.001.

    Abbreviations: SPA, spontaneous physical activity (R = 0.56, adjusted R2 0.27; n = 98 measurements in 49 cancer patients); ME, maximum exercise capacity (R = 0.67, adjusted R2 0.43; n = 66 measurements in 49 cancer patients); Hb, blood hemoglobin concentration (g/L); PF, physical functioning; BP, bodily pain.