Table 4.

Frequency of IRAEs

Grade 1/2
Grade 3/4
All n = 139Peptide n = 73No peptide n= 66All n = 139Peptide n = 73No peptide n = 66
None76 (55%)37 (51%)39 (59%)89 (64%)48 (66%)41 (62%)
One or more63 (45%)36 (49%)27 (41%)50 (36%)25 (34%)25 (38%)
Alveolitis1 (1%)1 (1%)01 (1%)01 (2%)
Arthralgia11 (8%)9 (12%)2 (3%)3 (2%)1 (1%)2 (3%)
Conjunctivitis2 (1%)02 (3%)000
Dermatitis40 (29%)22 (30%)18 (27%)8 (6%)7 (10%)1 (2%)
Enterocolitis4 (3%)2 (3%)2 (3%)24 (17%)14 (19%)10 (15%)
Hepatitis0002 (1%)2 (3%)0
Hypophysitis00013 (9%)1 (1%)12 (18%)
Hypothyroidism3 (2%)1 (1%)2 (3%)000
Episcleritis0001 (1%)1 (1%)0
Nephritis0001 (1%)01 (2%)
Pruritis35 (25%)19 (26%)16 (24%)000
Uveitis1 (1%)01 (2%)3 (2%)2 (3%)1 (2%)
Death0 (0%)000 (0%)00