Table 2.

Univariate analysis of posttreatment pathologic variables in relation to local recurrence and overall survival

Factor typeFactorCategoryn (%)% LR at 24 moP% alive at 24 moP
ClinicopathologicypT stageypT0-ypT238 (19)30.061890.04
ypT3, ypT4162 (81)1972
ypN stageypN0131 (65)90.001810.001
ypN147 (23)2569
ypN223 (12)4640
ypTNMNo residual tumor14 (7)00.0221000.004
Stage I19 (9)081
Stage II97 (49)1382
Stage III70 (35)2959
CRMNegative158 (79)8<0.001800.004
Positive43 (21)4358
HistologicTypeAdenocarcinoma137 (79)130.04750.02
Mucinous37 (21)3260
Differentiation gradeGood/moderate111 (63)120.04800.05
Poor66 (37)2661
Growth patternCircumscript25 (14)170.90590.35
Diffuse147 (86)1876
Lymphoid reactionNone/few101 (58)220.23670.19
Moderate56 (32)1575
Extensive16 (9)894
Eosinophilic infiltrateNone129 (74)190.85730.33
Moderate/extensive45 (26)1777
Lymphangio invasionNo163 (94)160.51750.04
Yes11 (6)3040
CalcificationNo126 (71)190.58750.56
Yes51 (29)1367
Tumor necrosisNo76 (43)60.02680.76
Yes99 (57)2275
  • NOTE: Patients with missing data were excluded from local recurrence and overall survival analysis.

    Abbreviation: LR, local recurrence.