Table 3.

Spearman correlation between EGFR expression and cytotoxicity of TKIs stratified by the gene amplification

EGFR pattern
Spearman r
Amplification (meanCN)ExpressionMedianMinMax
<3MT1147−0.25−0.680.05
MT976−0.36−0.590.01
MT478−0.36−0.70−0.02
Microarray (STF)−0.44−0.76−0.11
Microarray (MOV)−0.38−0.71−0.08
Real-time PCR−0.41−0.70−0.17
≥3MT1147−0.24−0.49−0.03
MT976−0.01−0.330.21
MT478−0.29−0.590.07
Microarray (STF)−0.28−0.50−0.06
Microarray (MOV)−0.29−0.60−0.09
Real-time PCR−0.31−0.56−0.03
AllMT1147−0.24−0.54−0.03
MT976−0.18−0.370.05
MT478−0.33−0.59−0.11
Microarray (STF)−0.37−0.57−0.07
Microarray (MOV)−0.32−0.62−0.06
Real-time PCR−0.36−0.63−0.14
  • NOTE: Median, min, and max Spearman r values for 12 drugs are shown.