Table 1.

mRNA levels of TNC, TNXB, and TNN in dermal neurofibromas, plexiform neurofibromas, and MPNSTs

GenesGene aliasesGene definitionDermal neurofibromas (n = 20)Plexiform neurofibromas (n = 14)MPNSTs (n = 10)P*
TNCHXBTenascin C (hexabrachion)1.00 (0.25-4.43)2.98 (0.26-8.31)4.95 (1.81-18.45)0.0003
TNXBTNXTenascin XB1.00 (0.12-3.09)1.75 (0.12-5.48)0.03 (0.00-0.39)0.00003
TNNTNNTenascin N1.00 (0.18-6.70)0.32 (0.01-5.92)0.44 (0.01-4.91)NS
  • Abbreviation: NS, not significant.

  • * Mann-Whitney U test: dermal neurofibromas versus plexiform neurofibromas versus MPNSTs.

  • Median (range) of gene mRNA levels.