Correlation of patients' antibody production and p53 mutations with class II haplotypes
| Patient no. | Anti-p53 antibody | p53 mutation codon/exon | DR-DQ1 | DR-DQ2 | DPB1 | DPB2 |
|---|---|---|---|---|---|---|
| 27 | No | Yes/220/6 | 1302-0609 | 0103-0501 | 0401 | 0201 |
| 40 | Yes | Yes/220/6 | 1201-0301 | 1201-0301 | 0101 | 3601 |
| 46 | No | No | 1601-0502 | 0301-0201 | 0401 | 0402 |
| 49 | No | No | 1501-0602 | 0101-0501 | 0401 | 0401 |
| 53 | Yes | Yes/220/6 | 1502-0601 | 0701-0303 | 1501 | 0301 |
| 55 | No | No | 0701-0201 | 1305-0301 | — | — |
| 56 | No | No | 1501-0602 | 1101-0301 | 3301 | 4101 |
| 58 | No | No | 1301-0603 | 0701-0303 | - | - |
| 59 | No | No | 0103-0301 | 0301-0201 | 0401 | 0201 |
| 62 | No | Yes/279/8 | 1501-0503 | 1401-0503 | 0401 | 1001 |
| 63 | No | No | 0103-0501 | 0301-0201 | 0401 | 0401 |
| 66 | Yes | Yes/248/7 | 0101-0501 | 0701-0303 | 3701 | 4601 |
| 69 | No | Yes/251/7 | 1101-0301 | 1101-0301 | 3701 | 3701 |
| 71 | No | No | 0701-0201 | 0301-0201 | 0201 | 1101 |
| 75 | No | No | 1503-0602 | 0302-0402 | 0201 | 0101 |
| 77 | No | No | 1302-0609 | 0701-0303 | 0402 | 0101 |
| 85 | No | No | 0101-0501 | 0701-0303 | 0401 | 0401 |
| 93 | No | No | 0701-0201 | 0701-0201 | - | - |
| 98 | No | No | 0301-0201 | 0402-0301 | 0402 | 0301 |
| 99 | No | Yes/306/8 | 1201-0301 | 0701-0201 | — | — |
| 100 | No | No | 0301-0201 | 0301-0201 | 0201 | 0402 |
| 102 | No | No | 0301-0201 | 1602-0502 | — | — |
| 107 | No | No | 0801-0301 | 0701-0201 | 0402 | 0301 |
| 168 | Yes | Yes/220/6 | 1503-0602 | 1102-0301 | 0401 | 0201 |
| 180 | No | No | 0701-0201 | 0402-0301 | — | — |
| 191 | No | No | 0401-0301 | 0101-0501 | 5101 | 1101 |
| 192 | No | Yes/249/7 | 0701-0201 | 0701-0201 | 1301 | 1401 |
| 200 | No | Yes/193/6 | 1401-0503 | 1503-0502 | 0301 | 1301 |
| 217 | No | No | 0401-0302 | 0404-0303 | 0401 | 0201 |
| 226 | Yes | Yes/272/8 | 0403/06-0302 | 0407-0301 | 0401 | 0301 |
| 230 | No | No | 1501-0602 | 0301-0201 | 0401 | 0301 |
| 233 | No | No | 0701-0201 | 1302-0501 | 1801 | 0101 |
| 242 | No | No | 0101-0501 | 1104-0301 | 0402 | 0402 |
| 244 | No | No | 0101-0501 | 0101-0501 | 0401 | 0402 |
| 245 | No | Yes/275/8 | 0101-0501 | 0701-0201 | 0401 | 0401 |
| 253 | No | No | 1602-0502 | 1303-0301 | 0201 | 1701 |
| 269 | No | No | 1502-0601 | 1502-0601 | 2301 | 4801 |
| 270 | No | No | 0102-0501 | 1103-0301 | 0401 | 0402 |
| 273 | No | No | 0301-0201 | 1302-0501 | 1101 | 4001 |
| 278 | No | No | 1302-0609 | 0901-0303 | 0101 | 1701 |
| 289 | No | No | 0901-0303 | 0102-0501 | 0401 | 0201 |
| 296 | Yes | Yes/278/8 | 0701-0201 | 0101-0501 | 0401 | 0301 |
| 309 | Yes | Yes/278/8 | 1101-0602 | 0102-0501 | 0201 | 0101 |
NOTE: Tumor DNA was isolated PCR-amplified for the class II loci listed above and then probed with horseradish peroxidase–labeled oligonucleotides as described in Materials and Methods (—, not determined).