Table 1.

Cumulative incidence of relapse and TRM

Patient no.Follow-up timeEventNo. at riskKM method
CR method
No. of relapsesNo. of censored observationsRFSKM CIRNo. of relapses or TRMNo. of censored observationsEFSCR CIRCR CIT
110Relapse10101 × (9/10) = 0.90 + 1 × (1/10) = 0.1101 × (9/10) = 0.90 + 1 × (1/10) = 0.10 + 1 × (0/10) = 0
220+Alive9010.9 × (9/9) = 0.90.1 + 0.9 × (0/9) = 0.1010.9 × (9/9) = 0.90.1 + 0.9 × (0/9) = 0.10 + 0.9 × (0/9) = 0
335Relapse8100.9 × (7/8) = 0.78750.1 + 0.9 × (1/8) = 0.2125100.9 × (7/8) = 0.78750.1 + 0.9 × (1/8) = 0.21250 + 0.9 × (0/8) = 0
440TRM7010.7875 × (7/7) = 0.78750.2125 + 0.7875 × (0/7) = 0.2125100.7875 × (6/7) = 0.6750.2125 + 0.7875 × (0/7) = 0.21250 + 0.7875 × (1/7) = 0.1125
550+Alive6010.7875 × (6/6) = 0.78750.2125 + 0.7875 × (0/6) = 0.2125010.675 × (6/6) = 0.6750.2125 + 0.675 × (0/6) = 0.21250.1125 + 0.675 × (0/6) = 0.1125
655Relapse5100.7875 × (4/5) = 0.630.2125 + 0.7875 × (1/5) = 0.37100.675 × (4/5) = 0.540.2125 + 0.675 × (1/5) = 0.34750.1125 + 0.675 × (0/5) = 0.1125
770TRM4010.63 × (4/4) = 0.630.37 + 0.63 × (0/4) = 0.37100.54 × (3/4) = 0.4050.3475 + 0.54 × (0/4) = 0.34750.1125 + 0.54 × (1/4) = 0.2475
871TRM3010.63 × (3/3) = 0.630.37 + 0.63 × (0/3) = 0.37100.405 × (2/3) = 0.270.3475 + 0.405 × (0/3) = 0.34750.2475 + 0.405 × (1/3) = 0.3825
980Relapse2100.63 × (1/2) = 0.3150.37 + 0.63 × (1/2) = 0.685100.27 × (1/2) = 0.1350.3475 + 0.27 × (1/2) = 0.48250.3825 + 0.27 × (0/2) = 0.3825
1090Alive1010.315 × (1/1) = 0.3150.685 + 0.315 × (0/1) = 0.685010.135 × (0/1) = 0.1350.4825 + 0.135 × (0/1) = 0.48250.3825 + 0.135 × (0/1) = 0.3825
• NOTE: +, censored time; RFS (SKMrel), KM estimate for relapse-free survival; KM CIR (CIKMrel), KM estimate of cumulative incidence of relapse; EFS (SKMrel,TRM), KM estimate for relapse- and TRM-free survival; CR CIR (SCRrel), CR estimate of cumulative incidence of relapse; CR CIT (CICRTRM), CR estimate of cumulative incidence of TRM.