Table 3.

Frequency comparisons of TAPP protein and mRNA in glioma cell lines and in surgically resected glioblastoma multiforme tissues as found in the studies presented here and elsewhere

TAPP geneGlioma cell lines/protein detection
GBM specimens/protein detection
GBM specimens/qPCR detection
Glioma cell lines/qPCR detection
GBM specimens/molecular detection
GBM specimens/microarray detection
Positive/total analyzed (% frequency)Positive/total analyzed (% frequency) reference sourcePositive/total analyzed (% frequency)Positive/total analyzed (% frequency)Positive/total analyzed (% frequency) reference sourcePositive/total analyzed (% frequency)
B-cyclin17/17 (100%)10/10 (100%)6/14 (43%)
EphA216/17 (94%)13/14 (93%), ref. 2210/11 (91%)10/14 (71%)
9/9 (100%), ref. 21
Her2/neu17/17 (100%)(76%) ref. 1611/11 (100%)N = 43 (81%), ref. 162/14 (14%)
IL13Rα217/17 (100%)11/11 (100%), ref. 4410/11 (91%)11/11 (100%), ref. 444/14 (29%)
GnT-V17/17 (100%)11/11 (100%)6/13 (46%), ref. 270/14 (0%)
GP10010/17 (59%)(45%) ref 169/11 (82%)8/21 (38%), ref. 12; 43 (46%), ref 160/14 (0%)
Mage-117/17 (100%)12/14 (86%), ref. 45; (38%) ref. 1611/11 (100%)8/21 (38%), ref. 1243 = n (40%), ref. 163/14 (21%)
Mart-113/17 (76%)4/11 (36%)0/14 (0%)
Survivin17/17 (100%)45/56 (80%), ref. 2510/11 (91%)1/14 (7%)
(83%) ref. 26
hTert17/17 (100%)10/10 (100%)30/43 (70%), ref. 230/14 (0%)
Trp-16/17 (35%)10/11 (91%)11/21 (52%), ref. 120/14 (0%)
Tyrosinase11/17 (65%)10/11 (91%)8/21 (38%), ref. 1214/14 (100%)
Aim-210/11 (91%)17/17 (100%)N = 43 (93%), ref. 180/14 (0%)
Gage-10/11 (0%)2/17 (12%)13/20 (65%), ref. 1314/14 (100%)
Sart-15/10 (50%), ref. 2410/11 (91%)17/17 (100%)14/14 (100%)
Trp-29/11 (82%)7/17 (100%)13/21 (62%), ref. 120/14 (0%)