Table 2.

Assessment of gene classifiers

Data set	Prediction rate	Sensitivity	Specificity	P*	OR
22-gene New Zealand classifier tested on German data
NZ data (training; SVM)	0.77 (0.66-0.86)	0.53 (0.33-0.73)	0.88 (0.77-0.95)	0.002	8.4 (3.5-21.4)
NZ data minus four genes not found in German data were removed from NZ data set (training; SVM)	0.72	0.38	0.87	0.011
German data (test; SVM)	0.71 (0.51-0.86)	0.62 (0.32-0.86)	0.79 (0.52-0.95)	0.002	5.9 (1.6-24.5)

19-gene German classifier tested on NZ data
German data (training; 3-NN)	0.84 (0.65-0.95)	0.85	0.83	<0.0001	24.1 (5.3-144.7)
German data minus five genes not found in NZ data were removed from German data set (training; 3-NN)	0.67	0.65	0.66	0.046
NZ data (test; 3-NN)	0.67 (0.55-0.78)	0.42 (0.22-0.64)	0.78 (0.65-0.89)	0.045	2.6 (1.2-6.0)