Table 3.

Results of immunostaining for Shh, Ptch, Smo, and Gli1 in endometrial carcinomas according to stage and histologic grade

Stage
Histologic grade
Total (77)
I + II (57)III + IV (20)1 (43)2 (16)3 (18)
Shh PI17.4 ± 21.221.9 ± 19.421.7 ± 23.712.8 ± 16.416.3 ± 15.318.6 ± 20.7
Cases, n (%)31 (51)12 (60)24 (56)8 (50)11 (61)43 (56)
Ptch PI11.8 ± 15.525.1 ± 19.9*11.8 ± 15.320.1 ± 22.918.1 ± 17.115.0 ± 17.6
Cases, n (%)23 (40)15 (75)18 (42)9 (56)11 (61)38 (49)
Smo PI4.9 ± 8.65.2 ± 9.64.2 ± 6.612.3 ± 14.20.6 ± 1.05.0 ± 8.8
Cases, n (%)12 (21)5 (25)9 (21)7 (43)1 (6)17 (22)
Gli1 PI5.3 ± 9.910.6 ± 15.64.4 ± 8.19.5 ± 14.69.6 ± 15.46.7 ± 11.7
Cases, n (%)14 (25)7 (35)9 (21)6 (38)6 (33)21 (27)
  • NOTE: Cases, n (%): number of positive cases and percentage in the group. Each PI is indicated by the mean ± SD.

  • * Significantly different from that of stage I + II (P < 0.05).

  • Significantly different from that of grade 1 or 2 (P < 0.05).