Table 4.

NF-κB activity in peripheral leukemia cells before and after bortezomib treatment

Patient no.NF-κB activity (ng/10 μg protein)
Pre6 h12 h24 h
1*5.5 ± 1.25.8 ± 1.82.0 ± 1.50.8 ± 0.3
27.6 ± 0.510.3 ± 2.41.8 ± 0.4
  • * Samples shipped to our institution prior to NF-κB determination.

  • Tumor cells isolated locally prior to NF-κB determination.