Table 3.

Course 1 toxicities possibly, probably, or likely related to 17-AAG (n = 12)

Toxicity typeGrade 1Grade 2Grade 3
Hemoglobin111
Neutrophils1
Leucocytes1
Fatigue1
Fever1
Odor11
Rash/desquamation1
Constipation2
Heartburn/dyspepsia1
Nausea21
Taste alteration1
Vomiting21
Hypoalbunimemia1
Alkaline phosphatase1
ALT3
AST2
GGT1
Hyperuricemia1
Abdominal pain1
Pain extremity-limb1
Pain head/headache1
Pain1
  • Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, γ-glutamyl transpeptidase.