Table 3.

Mean pharmacokinetic variables

CharacteristicsMean (SD)% Coefficient of variation
Cmax (μg/ML)
Tmax (h)155.44 (64.81)41.7
t1/2 (h)3.24 (1.40)43.3
AUC0-∞ (h μg/mL)317 (123)38.7
Vz (L)223926 (9237)38.6
Vss (L)4.10 (1.14)34.5
CL (L/h)4.40 (1.84)41.9
Mean residence time (h)0.0095 (0.0033)34.6
474 (164)34.5