Table 3.

FISH analysis of CTC

PatientCTC countAR copy numberX cen copy numberRatio*ERBB2 copy number17 cen copy numberRatioPloidy
A9111221Diploid
B253313-53-51.15Tetraploid
C272-32-313-43-41Tetraploid
D36111221Diploid
E50Amp2-3>103-43-41Tetraploid
F90Amp1>10221Diploid
G114221441Tetraploid
Amp2>103-43-41Tetraploid
H179Amp2-3>103-43-41Tetraploid
J561Amp1>10221Diploid
Amp2-3>103-53-51Tetraploid
  • NOTE: Ploidy was inferred from FISH signal counts.

    Abbreviations: cen, centromere; Amp, amplification of gene locus.

  • * Ratio of AR copy number to X centromere copy number.

  • Ratio of ERBB2 copy number to 17 centromere copy number.