Table 1.

Frequency of B-RAFsmt when compared with known clinical prognostic factors in stage IV melanoma patients receiving biochemotherapy

Clinical factorsB-RAFsmt (N = 20)B-RAFswt (N = 30)P
Age
    Mean ± SD43.4 ± 10.845.9 ± 11.80.629
    ≤5015190.386
    >50511
Gender
    Female480.740
    Male1622
ECOG
    0-18180.166
    21212
No. Met sites
    1-210200.239
    ≥31010
Met sites
    ST/LN/lung only2120.021
    Other1818
    CNS Met15280.100
LDH
    Mean ± SD500.4 ± 857.2295.2 ± 280.70.037
    ≤1905170.027
    >1901513
  • NOTE: B-RAFwt at V600E.

    Abbreviations: ECOG, Eastern Cooperative Oncology Group; ST, soft tissue; LN, lymph node; CNS, central nervous system.