Number of patients with possibly or probably related adverse events by maximum toxicity grade
| Event | Grade 1 | Grade 2 | Grade 3 | Grade 4 | Total | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Fever* | 8 | 4 | 1 | 0 | 13 | |||||
| Rigors* | 10 | 1 | 0 | 0 | 11 | |||||
| Headache* | 3 | 7 | 0 | 0 | 10 | |||||
| Somnolence | 6 | 3 | 0 | 0 | 9 | |||||
| Vomiting | 3 | 2 | 0 | 0 | 5 | |||||
| Nausea | 3 | 1 | 0 | 0 | 4 | |||||
| Hematuria | 3 | 0 | 0 | 0 | 3 | |||||
| Prothrombin decreased | 3 | 0 | 0 | 0 | 3 | |||||
| Abdominal pain | 1 | 1 | 0 | 0 | 2 | |||||
| Albuminuria | 2 | 0 | 0 | 0 | 2 | |||||
| EKG abnormal | 2 | 0 | 0 | 0 | 2 | |||||
| Hemorrhage nos | 2 | 0 | 0 | 0 | 2 | |||||
| Anemia | 0 | 1 | 0 | 0 | 1 | |||||
| Anorexia | 1 | 0 | 0 | 0 | 1 | |||||
| Coagulation time | 1 | 0 | 0 | 0 | 1 | |||||
| Increased | ||||||||||
| Concentration impaired | 1 | 0 | 0 | 0 | 1 | |||||
| Creatine phosphokinase | 1 | 0 | 0 | 0 | 1 | |||||
| Increased | ||||||||||
| Diarrhea | 1 | 0 | 0 | 0 | 1 | |||||
| Fatigue | 0 | 1 | 0 | 0 | 1 | |||||
| Myocardial ischemia | 1 | 0 | 0 | 0 | 1 | |||||
| Thrombophlebitis deep | 0 | 0 | 1 | 0 | 1 | |||||
| Tremor | 1 | 0 | 0 | 0 | 1 | |||||
| Urticaria | 1 | 0 | 0 | 0 | 1 | |||||
Abbreviation: nos, not otherwise specified.
↵* Probably related.