Table 3.

Clinical AEs reported by ≥10% patients (N = 74)

All reported AEs, n (%)
AEs classified as drug related by the investigator, n (%)
All gradesGrades 3-5All gradesGrades 3-5
Diarrhea38 (51)036 (49)0
Fatigue38 (51)5 (7)34 (46)4 (6)
Nausea32 (43)3 (4)32 (43)3 (4)
Anorexia20 (27)2 (3)19 (26)2 (3)
Dysgeusia20 (27)018 (24)0
Weight loss15 (20)1 (1)14 (19)1 (1)
Alopecia14 (19)013 (18)0
Chills13 (18)1 (1)9 (12)1 (1)
Constipation12 (16)08 (11)0
Muscle spasms12 (16)2 (3)12 (16)2 (3)
Dizziness11 (15)1 (1)5 (7)1 (1)
Vomiting11 (15)1 (1)9 (12)0
Pruritis10 (14)1 (1)1 (1)0
Headache9 (12)04 (6)0
Peripheral edema9 (12)02 (3)0
Upper respiratory tract infection9 (12)02 (3)0
Dry mouth8 (11)08 (11)0