Table 1.

Abstract inclusion algorithm

Was the abstract published during 2002?
Does the article describe an original trial in human subjects?
Is the abstract written in English?Yes, include abstract
No, exclude abstract
Does the article explicitly state that the trial is a phase II, phase I/II, or phase II/III trial?
Yes, include abstract
No, then
Does the abstract imply that the trial is the first test of activity of a given intervention previously only tested for safety?
Yes, include abstract
No, exclude abstract