Table 1.

RT-PCR expression of human Brachyury in human tumor cell lines

Tumor typeTumor cell lineBrachyury mRNA
LungH441++
NCI-H460++
H226+
NCI-H520+
SW900
ColonSW480++
SW620++
Colo 201+
Colo 205+
CaCo2+
SW403+
T-84+
SW948
SW1463
HT-29
SW1116
ProstateLNCAP+
PC-3+
DU145+
PancreaticCapan-2+
Paca-2
BxPC3
PANC-1
ASPC-1
BreastMCF-7
MA-MB-231
OvarianSW626++*
NIH-OVCAR3
SK-OV3
OsteosarcomaU2OS
  • NOTE: Expression of Brachyury mRNA is shown relative to the expression of β-actin as being negative (−), positive (+), or strongly positive (++).

  • * There is conflicting evidence that this cell line may be of colonic origin. See ref. 35.