Table 2.

Characteristics of subjects with germline BRCA2 mutations but no LOH in their prostate tumors at BRCA2

SubjectMutation carrierMutation descriptionLOH resultOther family members (cancer type, mutation-carrier status, LOH result)
22YesBRCA2 478 C>TNo LOHN/A
9YesBRCA2 767_768 ins ATNo LOHBrCa, +ve, LOH
16YesBRCA2 4075_4076 del GTNo LOHOvCa, +ve, no LOH
10YesBRCA2 8525 del CNo LOHBrCa,* +ve, LOH
  • * Breast tumor from prostate cancer affected subject 10.