Table 4.

Risk of pancreatic cancer associated with FasL or CASP8 genotypes by smoking

GenotypeNonsmokers
Smokers
Cases/controlsOR* (95% CI)Cases/controlsOR* (95% CI)
FasL −844C→T
    TT11/561.00 (Reference)4/231.03 (0.21-4.92)
    CT91/2791.63 (0.81-3.27)53/983.92 (1.54-9.97)
    CC149/3332.17 (1.08-4.35)89/11811.85 (4.44-31.57)
CASP8 −652 6N ins→del
    del/del12/451.00 (Reference)6/181.05 (0.27-4.12)
    ins/del68/2491.00 (0.49-2.06)43/744.33 (1.59-11.74)
    ins/ins171/3741.69 (0.86-3.35)97/1475.04 (2.19-11.63)
  • * Data were calculated by logistic regression, adjusted for sex, age, drinking, and diabetes mellitus history.

  • P < 0.05, test for homogeneity between smoking related ORs among the CT and TT genotypes.

  • P < 0.01, test for homogeneity between smoking-related ORs among the CC and TT genotypes.