Table 5.

Risk of pancreatic cancer associated with FASL or CASP8 genotypes by diabetes history

GenotypesWithout diabetes mellitus history
With diabetes mellitus history
Cases/controlsOR* (95% CI)Cases/controlsOR* (95% CI)
FasL −844C→T
    TT + CT137/4201.00 (Reference)22/361.93 (1.08-3.45)
    CC193/4191.42 (1.10-1.84)45/324.62 (2.80-7.64)
CASP8 −652 6N ins→del
    del/del + ins/del107/3511.00 (Reference)22/352.25 (1.25-4.06)
    ins/ins223/4881.49 (1.14-1.95)45/334.74 (2.83-7.94)
  • * Data were calculated by logistic regression, adjusted for sex, age, smoking, and drinking.

  • P < 0.05, test for homogeneity between diabetes mellitus history–related ORs among different FasL or CASP8 genotypes.