Table 1.

Selected transcripts up-regulated in prostate-infiltrating Treg

Probe IDFold increaseGene definitionGene symbolCellular component
Treg associated
211786_at122Tumor necrosis factor receptor superfamily, member 9 (4-1BB)TNFRSF9Membrane
234895_at95CTL-associated protein 4CTLA4Membrane
206486_at86Lymphocyte-activation gene 3LAG3Membrane
211269_s_at58IL-2 receptor-α (CD25)IL2RAMembrane
223851_s_at31Tumor necrosis factor receptor superfamily, member 18 (GITR)TNFRSF18Membrane
224211_at17Forkhead box P3FOXP3Nucleus
Cytokines
216876_s_at262IL-17AIL17AExtracellular
210354_at148IFNγIFNGExtracellular
207433_at116IL-10IL10Extracellular
205207_at29IL-6 (IFNβ2)IL6Extracellular
Cytokine receptors
202948_at254IL-1 receptor, type IIL1R1Membrane
1552912_a_at39IL-23 receptorIL23RMembrane
Chemokines
205476_at291Chemokine (C-C motif) ligand 20CCL20Extracellular
204103_at189Chemokine (C-C motif) ligand 4CCL4Extracellular
216598_s_at138Chemokine (C-C motif) ligand 2CCL2Extracellular
205114_s_at52Chemokine (C-C motif) ligand 3CCL3Extracellular
Chemokine receptors
206978_at111Chemokine (C-C motif) receptor 2CCR2Membrane
206991_s_at45Chemokine (C-C motif) receptor 5CCR5Membrane
206983_at17Chemokine (C-C motif) receptor 6CCR6Membrane
Toll-like receptors
206271_at310Toll-like receptor 3TLR3Membrane
220146_at26Toll-like receptor 7TLR7Membrane
  • NOTE: See Supplementary Tables S2 and S3 for complete data set.