Table 3.

Most frequent treatment-related (possibly, probably, or definitely related) adverse events (>10% of patients) by severity

Preferred termGrade 1, n (%)Grade 2, n (%)Grade 3, n (%)Grade 4, n (%)All active (n = 41), n (%)
Fatigue5 (12.2)9 (22.0)1 (2.4)15 (36.6)
Hypotension14 (34.1)14 (34.1)
Nausea12 (29.3)12 (29.3)
Pyrexia4 (9.8)1 (2.4)5 (12.2)