Table 2.

Characteristics of patients with MSS and MSI-H colorectal cancer

Clinicopathologic featuresFrequency, n (%)
P
MSS (n = 1,197)MSI-H (n = 223)
Sex
    Male596 (50.0)78 (35.0)<0.001
    Female595 (50.0)145 (65.0)
Age (y), median (range)70.0 (30.0-96.0)69.1 (37.0-93.0)0.258
Tumor location
    Left-sided834 (70.9)78 (35.0)<0.001
    Right-sided343 (29.1)145 (65.0)
Histologic subtype
    Mucinous89 (7.0)30 (13.5)0.001
    Nonmucinous1179 (93.0)193 (86.5)
Grade
    127 (2.3)4 (1.8)<0.001
    21010 (86.7)167 (75.9)
    3128 (11.0)49 (22.3)
T stage
    pT160 (5.2)2 (0.9)<0.001
    pT2189 (16.2)14 (6.3)
    pT3740 (63.5)159 (71.6)
    pT4176 (15.1)47 (21.2)
pN stage
    pN0587 (51.4)124 (56.1)0.344
    pN1308 (27.0)50 (22.6)
    pN2247 (21.6)47 (21.3)
Vascular invasion
    Absent834 (71.5)168 (76.7)0.155
    Present332 (28.5)51 (23.3)
TILs, mean no. cells ± SD8.2 ± 16.515.5 ± 30.9<0.001
Peritumoral lymphocytes
    Absent928 (79.6)164 (74.6)0.093
    Present238 (20.4)56 (25.5)
Survival time, median (95% CI)73.0 (62.0-85.0)142 (137.0-ne)<0.001