Table 1.

Patient and tumor characteristics

CharacteristicSetting of breast cancer detection
P
Screening (n = 247), n (%)Outside of screening (n = 989), n (%)
Age at diagnosis (y)
    ≤392 (1)82 (8)<0.0001
    40-4930 (12)238 (24)
    50-59158 (64)150 (15)
    60-6948 (20)198 (20)
    ≥709 (4)321 (32)
Primary tumor diameter (cm)
    ≤0.512 (5)8 (1)<0.0001
    0.6-1.071 (30)123 (13)
    1.1-2.0114 (48)384 (40)
    2.1-5.041 (17)395 (41)
    >5.01 (0)47 (5)
    NA832
No. positive axillary nodes
    0186 (77)573 (62)<0.0001
    1-344 (18)231 (25)
    4-99 (4)89 (10)
    ≥102 (1)27 (3)
    NA669
Histologic grade
    169 (35)155 (21)<0.0001
    294 (48)354 (48)
    332 (16)223 (30)
    NA52257
Histologic type
    Ductal185 (75)759 (77)0.030
    Lobular27 (11)142 (14)
    Special35 (14)88 (9)
    NA00
ER expression
    Negative54 (22)287 (29)0.021
    Positive189 (78)681 (69)
    NA621
Ki-67 expression
    Low-moderate151 (71)567 (63)0.035
    High63 (29)335 (37)
    NA3387
PR expression
    Negative85 (37)426 (44)0.052
    Positive145 (63)542 (56)
    NA1721
HER2 amplification
    Negative209 (85)789 (80)0.085
    Positive38 (15)200 (20)
    NA00
HER2 expression
    Negative195 (84)766 (80)0.22
    Positive38 (16)190 (20)
    NA1840
TP53 expression
    Negative-low165 (83)723 (81)0.60
    Positive34 (17)166 (19)
    NA48100
Adjuvant systemic therapy
    Not given184 (75)553 (57)<0.0001
    Given60 (25)414 (43)
    NA322