Table 1.

Prognostic clinicopathologic variables as predictors for DSS in 335 NSCLS (univariate analysis, log-rank test)

CharacteristicsPatients [n (%)]Median survival (mo)5-y survival (%)P
Age (y)
    ≤65156 (47)104570.62
    >65179 (53)NR58
Sex
    Female82 (25)127650.19
    Male253 (75)8455
Smoking
    Never15 (5)19430.13
    Present215 (64)NR60
    Previous105 (31)8454
Performance status
    Normal197 (59)NR620.04
    Slightly reduced120 (36)6152
    In bed <50%18 (5)3640
Weight loss
    <10%303 (90)127570.92
    >10%32 (10)NR57
Histology
    SCC191 (57)NR650.30
    Adenocarcinoma95 (28)5244
    Bronchioloalveolar carcinoma18 (5)NR67
    Large cell carcinoma31 (9)8454
Differentiation
    Poor138 (41)48480.001
    Moderate144 (43)NR64
    Well53 (16)NR65
Surgical procedure
    Lobectomy + wedge*243 (73)NR610.0009
    Pneumonectomy92 (27)3546
Stage
    I212 (63)NR68<0.00001
    II91 (27)4146
    IIIA32 (10)1822
Tumor status
    190 (27)NR750.002
    2218 (65)8452
    327 (8)4243
Nodal status
    0232 (69)NR66<0.00001
    176 (23)3743
    227 (8)1820
Surgical margins
    Free307 (92)127580.34
    Not free28 (8)6451
Vascular infiltration
    No284 (85)NR610.0005
    Yes51 (15)2535
Postoperative radiotherapy
    No276 (82)NR610.002
    Yes59 (18)4142
  • Abbreviation: NR, not reached.

  • * Wedge (n = 10).