Table 1.

Baseline demographic characteristics of the patients who underwent FISH for EGFR, alone and in combination with HER2, and KRAS mutational analysis

CharacteristicEGFR by FISH
EGFR and HER2 by FISH
No. patients (%)
Sex
    Male49 (56)37 (58)
    Female38 (44)27 (42)
Age, y
    Median58.656.2
    Range25.7-80.125.7-80.1
Cetuximab doses (mg/m2)
    25075 (86)55 (86)
    ≥25012 (14)9 (14)
Treatment
    Cetuximab monotherapy18 (21)12 (19)
    Cetuximab and irinotecan69 (79)52 (81)
KRAS mutation status
    Wild-type58 (67)44 (69)
    Mutant29 (33)20 (31)