Table 2.

Association of 15 reported prostate cancer risk SNPs with clinicopathologic variables in prostate cancer patients

SNPsChrPosition*Alleles
Frequency of risk allele in controls n = 486Aggressiveness
Stage
Age at diagnosis (y)
ReferenceRiskFrequency of risk alleles
PFrequency of risk alleles
PFrequency of risk alleles
P
More N = 1,017Less N = 528T3/N+/M+ N = 714T2/N0/M0 N = 528≥65<65
rs26607533p1287,193,364CT0.120.140.130.530.130.140.750.140.140.72
rs93645546q25160,804,075CT0.270.310.270.040.300.280.350.280.300.47
rs104865677p1527,749,803TC0.800.780.780.650.780.780.790.760.790.11
rs64656577q2197,654,263TC0.460.480.490.570.480.480.790.460.490.22
rs169019798q24 (2)128,194,098CA0.040.050.050.630.050.060.340.040.060.26
rs69832678q24 (3)128,482,487TG0.500.560.580.400.560.580.220.590.560.20
rs14472958q24 (1)128,554,220CA0.080.140.120.270.140.130.150.120.130.50
rs15718019q33121,506,927GT0.230.260.260.640.260.270.550.270.260.42
rs1099399410q1151,219,502CT0.430.470.460.590.490.460.180.450.470.29
rs496241610q26126,686,862AG0.280.310.330.380.320.320.810.320.320.89
rs1089644911q1368,751,243AG0.520.570.570.860.570.580.660.570.570.79
rs443079617q1233,172,153CT0.510.580.580.740.570.580.700.560.580.33
rs185996217q24.366,620,348TG0.480.510.510.950.530.510.280.500.520.45
rs273583919q1356,056,435AG0.860.860.890.030.860.890.020.870.880.56
rs5945619Xp1151,074,708AG0.330.420.360.020.430.370.050.400.400.98
  • Abbreviation: Chr, chromosome.

  • * Build35.

  • Risk alleles are based on the previously published studies.