Frequency of grades 3 and 4 toxicities, at least possibly related to study treatment, occurring during the first four cycles of study treatment, among patients in ovarian cancer cohort (n = 24)
| Toxicity | Grade 3, n (%) | Grade 4, n (%) |
|---|---|---|
| Febrile neutropenia | 1 (4) | 1 (4) |
| Neutropenia | 4 (17) | 17 (71) |
| Lymphopenia | 9 (38) | 0 |
| WBC count | 13 (54) | 4 (17) |
| Anemia | 3 (13) | 0 |
| Thrombocytopenia | 0 | 0 |
| Rash/desquamation | 1 (4) | 0 |
| Dehydration | 1 (4) | 0 |
| Infection, without neutropenia | 1 (4) | 0 |
| International normalized ratio | 1 (4) | 0 |