Table 1.

Patient demographics

Part 1Part 2
n1715
Male/female13/48/7
Mean (range) age56 (31-72)48 (32-68)
Performance status 0:1:27:10:09:6:0
Tumor typeSarcoma 3Melanoma 15 (13 cutaneous, 1 ocular, and 1 clear cell sarcoma of soft tissue)
Melanoma 3
Colorectal 3
Others 8
Previous treatmentPretreated but no DTIC/temozolomideChemonaive