Table 2.

Comparison of HER-2 gene amplification by FISH with HER-2 protein expression by IHC

FISHIHC
0 (%)1+ (%)2+ (%)3+ (%)Total
Negative237 (94.8)99 (81.8)36 (48)8 (3)380
Positive13 (5.2)21 (18.2)39 (52)258 (97)331
Total250 (100)120 (100)75 (100)266 (100)711