Table 1.

CSC analysis and patient survival according to CSC generation, CD133, and CD133+/Ki67

Outcome variableNo. CSC generation (n = 30)CSC generation (n = 14)CD133 < 2% (n = 25)CD133 ≥ 2% (n = 19)CD133+/Ki67 (n = 34)CD133+/Ki67+ (n = 10)
Overall survival
    Median duration (mo)14.0 (11.0-18.0)8.0 (4.0-11.5)14.0 (11.0-18.0)10.5 (7.5-12.5)12.25 (11.0-16.0)6.75 (3.0-14.0)
    Rate at 1 y (%)56.7 (38.9-74.4)21.4 (5.2-44.8)56 (34.8-72.7)31.6 (10.7-52.5)50.0 (33.2-66.8)30.0 (1.6-58.4)
    HR for death1.003.6 (1.7-7.4)1.002.2 (1.1-4.2)1.002.7 (1.2-5.9)
Progression-free survival
    Median duration (mo)9.0 (7.0-12.0)3.5 (2.0-6.0)10.0 (6.0-12.0)5.0 (3.0-7.0)8.0 (6.0-11.0)2.5 (1.0-6.0)
    Rate at 6 mo (%)70 (53.6-86.4)14.2 (0-32.6)68.0 (49.7-86.3)31.6 (10.7-52.5)61.7 (45.4-78)20.0 (0-44.8)
    HR for progression and death1.003.4 (1.7-6.8)1.002.1 (1.1-4.0)1.003.1 (1.4-6.5)
  • NOTE: Numbers in parenthesis are 95% CI.