Table 3.

Bioinformatic analysis of array CGH data from MPNST samples

A. Combinations of three deleted and/or amplified genes present in ≥7 MPNST samples including the NF1 gene
Deleted genesAmplified genesNumber of combinations
NF1HMMRMMP1310
NF1HMMRp16-INK4a9
NF1MMP13p16-INK4a7
NF1p16-INK4aBIRC57
NF1p16-INK4a8
NF1BIRC5ITGB48
NF1ITGB4CCND17
NF1ITGB4TERT9
NF1ITGB4TP737
NF1TERTTP737
ITGB4TERTTP737
HGFMETPDGFRA7
B) Combinations of three deleted and/or amplified genes present in ≥6 MPNST samples excluding the NF1 gene
Deleted genesAmplified genes
Number of combinations
ITGB4TERTCCND6
ITGB4TERTTP737
BIRC5ITGB4TERT6
p16-INK4aITGB4TERT6
p16-INK4aBIRC5ITGB46
MMP13BIRC5ITGB46
HMMRp16-INK4aITGB46
HMMRMMP13p16-INK4a6
HGFMETPDGFRA7
HGFMETCCNE26
HGFPDGFRACCNE26
METPDGFRACCNE26