Table 2.

Clinicopathologic characteristics of the 4,046 breast cancer tumors

CharacteristicLuminal′
Luminal/HER2+
HER2+/ER−PR−
TNP method
Core Basal method
Unassigned (n = 302)
Basal (TNP)
Basal (Core Basal)
5NP
Total n = 2,625Total n = 222Total n = 258Total n = 639Total n = 336Total n =303Total n = 302
Age, yn (% within subtype)n (% within subtype)n (% within subtype)n (% within subtype)n (% within subtype)n (% within subtype)n (% within subtype)
>40184 (7.0)21 (9.5)37 (14.3)115 (18.0)71 (21.1)44 (14.5)23 (7.6)
40-49476 (18.1)49 (22.1)45 (17.4)149 (23.3)79 (23.5)70 (23.1)48 (15.9)
50-65921 (35.1)78 (35.1)112 (43.4)209 (32.7)109 (32.4)100 (33.0)115 (38.1)
>651,044 (39.8)74 (33.3)64 (24.8)166 (26.0)77 (22.9)89 (29.4)116 (38.4)
Graden (% within subtype)n (% within subtype)n (% within subtype)n (% within subtype)n (% within subtype)n (% within subtype)n (% within subtype)
1174 (6.6)4 (1.8)2 (0.8)12 (1.9)1 (.3)11 (3.6)19 (6.3)
21,244 (47.4)56 (25.2)53 (20.5)115 (18)35 (10.4)80 (26.4)114 (37.7)
31,082 (41.2)155 (69.8)196 (76)488 (76.4)293 (87.2)195 (64.4)148 (49)
Unknown125 (4.8)7 (3.2)7 (2.7)24 (3.8)7 (2.1)17 (5.6)21 (7)
Tumor size, cmn (% within subtype)n (% within subtype)n (% within subtype)n (% within subtype)n (% within subtype)n (% within subtype)n (% within subtype)
>21,455 (55.4)90 (40.5)105 (40.7)284 (44.4)152 (45.2)132 (43.6)159 (52.6)
2-51,041 (39.7)118 (53.2)127 (49.2)300 (46.9)155 (46.1)145 (47.9)111 (36.8)
>5106 (4.0)13 (5.9)20 (7.8)53 (8.3)28 (8.3)25 (8.3)27 (8.9)
Unknown23 (0.9)1 (0.5)6 (2.3)2 (0.3)1 (.3)1 (.3)5 (1.7)
LVIn (% within subtype)n (% within subtype)n (% within subtype)n (% within subtype)n (% within subtype)n (% within subtype)n (% within subtype)
Positive1,100 (41.9)133 (59.9)137 (53.1)259 (40.5)135 (40.1)124 (40.9)121 (40.1)
Negative1,406 (53.6)84 (37.8)113 (43.8)351 (54.9)185 (55.1)166 (54.8)166 (55)
Unknown119 (4.5)5 (2.3)8 (3.1)29 (4.5)16 (4.8)13 (4.3)15 (5)
Percentage of positive/total examined axillary lymph nodes (%)n (% within subtype)n (% within subtype)n (% within subtype)n (% within subtype)n (% within subtype)n (% within subtype)n (% within subtype)
01,412 (54.8)90 (40.5)109 (42.2)378 (59.2)204 (60.7)174 (57.4)172 (57.0)
0-25578 (22.0)46 (20.7)60 (23.3)127 (19.9)66 (19.6)61 (20.1)65 (21.5)
>25511 (19.5)72 (32.4)78 (30.2)112 (17.5)55 (16.4)57 (18.8)52 (17.2)
  • NOTE: Subtypes are defined by the TNP and Core Basal method.

    Abbreviation: LVI, lymphovascular invasion.