Table 4.

Cox regression analyses on basal (TNP) tumors

A. Cox regression analysis on 575 basal (TNP) tumors with sufficient information for the clinicopathologic covariates: age, tumor size, grade, lymphovascular invasion, and percentage positive among total examined axillary lymph nodes. Likelihood ratio test, P = 0.0127, df = 1
VariablesHazard ratio (95% CI)
Age, y
    40-49 vs ≤401.13 (0.74-1.74)
    50-65 vs ≤401.01 (0.67-1.53)
    >65 vs ≤401.11 (0.71-1.74)
Grade
    3 vs (2 and 1)1.31 (0.86-1.97)
Lymphovascular invasion
    Positive vs negative1.72 (1.21-2.44)
Tumor size, cm
    2-5 vs ≤21.68 (1.22-2.32)
    >5 vs ≤21.72 (1.04-2.84)
Percentage of positive/total number of dissected axillary lymph nodes
    0-25 vs 01.57 (1.07-2.30)
    >25 vs 02.64 (1.77-3.96)
Breast cancer subtype
    Basal (Core Basal) vs 5NP1.47 (1.08-1.99)
B. Cox regression analysis on the 95 basal (TNP) tumors treated with anthracycline-based (AC or FAC) adjuvant chemotherapy with sufficient information for the clinicopathologic covariates: age, tumor size, grade, lymphovascular invasion, and percentage positive among total examined axillary lymph nodes. Likelihood ratio test, P = 7.41 × 10−5, df = 1
Variables
Hazard ratio (95% CI)
Age, y
    ≥50 vs <501.48 (0.73-3.00)
Grade
    3 vs (2 and 1)0.38 (0.11-1.27)
Lymphovascular invasion
    Positive vs negative1.19 (0.46-3.07)
Tumor size, cm
    >2 vs ≤22.20 (0.98-4.96)
Percentage of positive/total number of dissected axillary lymph nodes
    0-25 vs 00.68 (0.20-2.28)
    >25 vs 05.07 (1.84-14.0)
Breast cancer subtype
    Basal (Core Basal) vs 5NP4.26 (2.00-9.08)