Table 1.

Expression of alternate growth factor receptors by Western blot analysis

EGFRpEGFRHER2HER3HER4 p180HER4 p80IGF-1RPDGFR-αPDGFR-βc-METFGFR3
JP+++++++++NT
BV+++++++++++++
UC5+++++++++++++++++
UC9+++++NT++++++*
UC14++++++++++++*
KU7++++++++++++++++++++
UC3+++++++++++++++++
UC6++++++++++++++++++
UC13+++++++++++++++
  • NOTE: Protein expression is rated as follows: −, none; +, weak; ++, moderate; +++, strong. Abbreviation: NT, not tested; HER4 p180, intact receptor with band at 180 kDa; HER4 p80, cleaved receptor with band at 80 kDa.

  • * FGFR3 mutations present (S249C).