Table 1.

Characteristics of RSCLs (Raji, RL, and SUDHL-4) and RRCLs (Raji 2R, Raji 4RH, RL 4RH, SUDHL-4 2R, and SUDHL-4 4RH)

Cell lineVariantCD20 SABCRituximab-mediated killing
CDCADCCDirect apoptosis
RajiParental241,187++++++
2R136,794+
4RH225,600+
RLparental293,512++++++
4RH113,316+
SU-DHL-4Parental127,334+++++
2R51,747+
4RH89,088+
  • Abbreviations: SABC, surface antigen binding capacity; CDC, complement-dependent cytotoxicity; ADCC, antibody-dependent cellular cytotoxicity.