ieTIL subtypes in normal cervix and cervical cancers
| Statistics | CD3+CD8+CD57− | FoxP3+ | CD3+CD8+/FoxP3+ | CD3+CD8− | CD3+CD8+/CD3+CD8− | CD3+CD8+CD57+ | CD3+CD57+ | CD8+CD57+ | CD57+ | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CD8+* | Treg | CD8+/Treg ratio | CD4+ | CD8+/CD4+ ratio | NKT1 | NKT2 | NK1 | NK2 | ||||||||||
| Normal epithelium | ||||||||||||||||||
| Mean | 60.1 | 0.9 | 138.2 | 23.4 | 3.2 | 3.1 | 1.6 | 0.4 | 0.2 | |||||||||
| SE | 12.0 | 0.3 | 39.8 | 3.6 | 0.9 | 1.1 | 0.8 | 0.2 | 0.2 | |||||||||
| Median† | 48.5 | 0.8 | 97.2 | 25.0 | 2.6 | 2.0 | 0.7 | 0.2 | 0.0‡ | |||||||||
| SD | 33.8 | 0.8 | 112.5 | 10.3 | 2.4 | 3.0 | 2.2 | 0.5 | 0.4 | |||||||||
| Minimum | 19.4 | 0.0 | 10.7 | 9.1 | 0.7 | 0.0 | 0.0 | 0.0 | 0.0 | |||||||||
| Maximum | 111.3 | 2.0 | 328.0 | 40.0 | 8.0 | 8.5 | 6.2 | 1.3 | 1.1 | |||||||||
| Cervical cancer | ||||||||||||||||||
| Mean | 187.4 | 5.9 | 79.9 | 65.9 | 3.8 | 19.1 | 5.2 | 0.3 | 1.0 | |||||||||
| SE | 21.9 | 0.7 | 15.2 | 6.7 | 0.5 | 2.7 | 1.0 | 0.1 | 0.2 | |||||||||
| Median† | 95.3 | 3.9 | 26.1 | 39.0 | 2.4 | 7.1 | 2.5 | 0.0‡ | 0.0‡ | |||||||||
| SD | 221.6 | 6.6 | 146.5 | 67.8 | 5.1 | 27.4 | 10.0 | 0.6 | 1.6 | |||||||||
| Minimum | 1.5 | 0.2 | 1.7 | 4.7 | 0.2 | 0.0 | 0.0 | 0.0 | 0.0 | |||||||||
| Maximum | 1,186.7 | 45.2 | 986.0 | 382.8 | 38.8 | 150.2 | 65.6 | 2.7 | 9.0 | |||||||||