Table 2.

ieTIL subtypes in normal cervix and cervical cancers

StatisticsCD3+CD8+CD57
FoxP3+
CD3+CD8+/FoxP3+
CD3+CD8
CD3+CD8+/CD3+CD8
CD3+CD8+CD57+
CD3+CD57+
CD8+CD57+
CD57+
CD8+*TregCD8+/Treg ratioCD4+CD8+/CD4+ ratioNKT1NKT2NK1NK2
Normal epithelium
    Mean60.10.9138.223.43.23.11.60.40.2
    SE12.00.339.83.60.91.10.80.20.2
    Median48.50.897.225.02.62.00.70.20.0
    SD33.80.8112.510.32.43.02.20.50.4
    Minimum19.40.010.79.10.70.00.00.00.0
    Maximum111.32.0328.040.08.08.56.21.31.1
Cervical cancer
    Mean187.45.979.965.93.819.15.20.31.0
    SE21.90.715.26.70.52.71.00.10.2
    Median95.33.926.139.02.47.12.50.00.0
    SD221.66.6146.567.85.127.410.00.61.6
    Minimum1.50.21.74.70.20.00.00.00.0
    Maximum1,186.745.2986.0382.838.8150.265.62.79.0
  • * These designations of the different ieTILs will be used in the text.

  • Used as a cutoff value.

  • The majority of cases lacked these cells.